by author Publications by date

2021

  • Korstanje, R., Peters LL., Krasinski SD., Churchill GA.
    The Jackson Laboratory Nathan Shock Center: impact of genetic diversity on aging.
    Geroscience. 2021 Jul 23;. doi: 10.1007/s11357-021-00421-2. [Epub ahead of print] PubMed PMID: 34297313

    [ Pubmed ]

    [full text]

  • Young K, Eudy E., R Bella, Loberg M, Stearns T., Devyani S, Velten L, Haas S., Filippi, M., Trowbidge, J.
    Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
    Cell Stem Cell. 2021 Aug 5;28(8):1473-1482.e7. doi: 10.1016/j.stem.2021.03.017. Epub 2021 Apr 12.

    [ Pubmed ]

    [full text]

  • Takemon Y., Chick JM., Gerdes Gyuricza I, Selley DA, Devuyst O. Gygi SP., Churchill GA., Korstanje R.
    Proteomic and transcriptomic profiling reveal different aspects of aging in the kidey
    Elife. 2021 Mar 9;10:e62585. doi: 10.7554/eLife.62585.

    [ Pubmed ]

    [full text]

2020

  • Khokhar ES, Borikar S, Eudy E, Stearns T, Young K, Trowbridge JJ
    Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation.
    Exp Hematol. 2020 Feb;82:43-52.e4. doi: 10.1016/j.exphem.2020.01.014. Epub 2020 Feb 1

    [ Pubmed ]

    [full text]

  • Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, White CC, De Jager PL, Schneider JA, Bennett DA, Seyfried NT; Alzheimer’s Disease Genetics Consortium, Chesler EJ, Hadad N, Hohman TJ, Kaczorowski CC
    Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia
    Cell Rep. 2020 Sep 1;32(9):108091. doi: 10.1016/j.celrep.2020.108091

    [ Pubmed ]

    [full text]

  • Rong Yuan, CJM Musters, Yun Zhu, Tracy R. Evans, Yujie Sun, Elissa Chesler, Luanne Peters, David E Harrison, Andrzej Bartke
    Genetic differences and longevity-related phenotypes influence lifespan and lifespan variation in a sex specific manner in mice
    Aging Cell. 2020 Oct 26;e13263. doi: 10.1111/acel.13263

    [ Pubmed ]

    [full text]

  • Jonathan Y An, Kristopher A Kerns, Andrew Ouellette, Laura Robinson, H Douglas Morris, Catherine Kaczorowski, So-Il Park, Title Mekvanich, Alex Kang, Jeffrey S McLean, Timothy C Cox, Matt Kaeberlein
    Rapamycin rejuvenates oral health in aging mice
    eLife 2020;9:e54318 doi: 10.7554/eLife.54318

    [ Pubmed ]

    [full text]

  • Garrett MR, Korstanje R.
    Using Genetic and Species Diversity to Tackle Kidney Disease.
    Trends Genet. 2020 Jul;36(7):499-509. doi: 10.1016/j.tig.2020.04.001. Epub 2020 Apr 30.

    [ Pubmed ]

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2019

  • Haque S, Ames RM, Moore K, Pilling LC, Peters LL, Bandinelli S, Ferrucci L, Harries LW
    circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan
    Geroscience. 2019 Dec 6. doi: 10.1007/s11357-019-00120-z

    [ Pubmed ]

    [full text]

  • Bubier JA, Sutphin GL, Reynolds TJ, Korstanje R, Fuksman-Kumpa A, Baker EJ, Langston MA, Chesler EJ
    Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species
    PLoS One. 2019 Apr 12;14(4):e0214523. doi: 10.1371/journal.pone.0214523 PMID: PMC6461221

    [ Pubmed ]

    [full text]

  • Mesner LD, Calabrese GM, Al-Barghouthi B, Gatti DM, Sundberg JP, Churchill GA, Godfrey DA, Ackert-Bicknell CL, Farber CR
    Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass
    PLoS Genet. 2019 May 1;15(5):e1008123. doi: 10.1371/journal.pgen.1008123. eCollection 2019 May. PMID: 31042701

    [ Pubmed ]

    [full text]

  • Alghamdi SM, Sundberg BA, Sundberg JP, Schofield PN, Hoehndorf R.
    Quantitative evaluation of Ontology design patterns for combining pathology and anatomy ontologies
    Sci Rep. 2019 Mar 11;9(1):4025. doi:10.1038/s41598-019-40368-1. PMID: 30858527

    [ Pubmed ]

    [full text]

  • Loberg MA, Bell RK, Goodwin LO, Eudy E, Miles LA, SanMiguel JM, Young K, Bergstrom DE, Levine RL, Schneider RK, Trowbridge JJ.
    Sequencially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis
    Leukemia. 2019 Jan 28. doi: 10.1038/s41375-018-0368-6. [Epub ahead of print]

    [ Pubmed ]

    [full text]

  • Schmitt EE, Johnson EC, Yusifova M, Bruns DR.
    The renal molecular clock: broken by aging restored by exercise
    Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1087-F1093. doi: 10.1152/ajprenal.00301.2019. Epub 2019 Aug 28.

    [ Pubmed ]

    [full text]

2018

  • Thompson MJ, Chwiałkowska K, Rubbi L, Lusis AJ, Davis RC, Srivastava A, Korstanje R, Churchill GA, Horvath S, Pellegrini M
    A Multi-tissue full lifespan epigenetic clock for mice
    Aging (Albany NY). 2018 Oct 21;10(10):2832-2854. doi: 10.18632/aging.101590. PMID:30348905

    [ Pubmed ]

    [full text]

  • Backer G, Eddy S, Sheehan SM, Takemon Y, Reznichenko A, Savage HS, Kretzler M, Kostanje R
    FAR2 is Associated with Kidney Disease in Mice and Humans
    Physiologenomics. 2018 Apr 13 doi:1152/physiolgenomics.00118.2017

    [ Pubmed ]

    [PMCID 29652635]

2017

  • Lee BP, Curic I, George-Pandeth A, Flurkey K, Harrison DE, Yan R, Peters LL, Kuchel GA, Melzer D, Harries LW
    MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice
    Sci Rep. 2017 Mar 17;7:44620. doi: 10.1038/srep44620

    [PMCID PMC5356331]

    [full text]

  • Sutphin GL, Backer G, Sheehan S, Bean S, Corban C, Liu T, Peters MJ, van Merus JBJ, Murabito JM, Johnson AD, Korstanje R, Cohorts for Heart & Aging Research in Genomic Epidemiology Consortium Gene Expression Working Group
    Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity
    Aging Cell, 2017 Aug;16(4):672-682. doi: 10.1111/acel.12595.

    [ PMCID PMC5506438 ]

    [full text]

  • Tyler AL, Ji B, Gatti DM, Munger SC, Churchill GA, Svenson KL, Carter GW
    Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice
    Genetics. 2017 Jun;206(2):621-639. doi: 10.1534/genetics.116.198051

    [ PMCID: PMC5499176 ]   7 Citations

     

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2016

  • Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ
    Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span
    J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):170-7. doi: 10.1093/gerona/glu223

    [PMCID:PMC4707687]

    [full text]

    [ Epub 2014 Dec 22 ]

  • Korstanje R, Deutsch K, Balanos-Palmieri P, Hanke N, Schroder, P, Staggs L, Brasen JH, Roberts IS, Sheehan S, Savage H, Haller H, Schiffer M
    Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria
    J Am Soc Nephrol. 2016 Nov;27(11):3271-3277

    [ PMCID: PMC5084883 ]

    [full text]

  • Lee BP, Pilling LC, Emond F, Flurkey K, Harrison DE, Yuan R, Peters LL, Kuchel GA, Ferrucci L, Melzer D, Harries LW
    Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans
    Aging Cell. 2016 Jun 30. doi: 10.1111/acel.12499

    [ Pubmed ]

    [Epub ahead of print]

  • Sutphin GL, Mahoney JM, Sheppard K, Walton DO, Korstanje R
    WORMHOLE: Novel Least Diverged Ortholog Prediction through Machine Learning
    PLoS Comput Biol. 2016 Nov 3;12(11):e1005182. doi: 10.1371/journal.pcbi.1005182.

    [ PMCID: PMS5094675 ]

    [full text]

  • Young K, Borikar S, Bell R, Kuffler L, Phillip V, Trowbridge JJ
    Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging
    J Exp Med. 2016 Oct 17;213(11):2259-2267. Epub 2016 Oct 10.

    [ PMCID: PMC5068232]

    [full text]

2015

  • Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL
    Aging Research Using Mouse Models
    Curr Protoc Mouse Biol. 2015 Jun 1;5(2):95-133. doi: 10.1002/9780470942390.mo140195

    [PMCID: PMC4590775]

    [full text]

  • Aziz MH, Chen X, Zhang Q, DeFrain C, Osland J, Luo Y, Shi X, Yuan R
    Suppressing NRIP1 inhibits growth of breast cancer cells in vitro and in vivo
    Oncotarget. 2015 Nov 24;6(37):39714-24. doi: 10.18632/oncotarget.5356

    [PMCID: PMC4741857]

    [ Full text ]

  • Bogue MA, Churchill GA, Chesler EJ
    Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database
    Mamm Genome. 2015 Oct;26(9-10):511-20. doi: 10.1007/s00335-015-9595-6

    [PMCID: PMC4602074]

    [full text]

    [ Epub 2015 Aug 19 ]

  • Noordmans GA, Hillebrands JL, van Goor H, Korstanje R
    A roadmap for the genetic analysis of renal aging
    Aging Cell. 2015 Oct;14(5):725-33. doi: 10.1111/acel.12378

    PMCID: PMC4568960

    [full text]

    [ Epub 2015 Jul 29 ]

  • Reznichenko A, Korstanje R
    The role of platelet-activating factor in mesangial pathophysiology
    Am J Pathol. 2015 Apr;185(4):888-96. doi: 10.1016/j.ajpath.2014.11.025

    PMCID: PMC4380849

    [full text]

    [ Epub 2015 Feb 2 ]

  • Yuan R, Gatti DM, Krier R, Malay E, Schultz D, Peters LL, Churchill GA, Harrison DE, Paigen B
    Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1
    J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):817-26. doi: 10.1093/gerona/glu114

    PMCID: PMC4481683

    [full text]

    [ Epub 2014 Jul 28 ]

2014

  • Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA
    Quantitative trait locus mapping methods for diversity outbred mice
    G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748

    PMCID: PMC4169154

    [full text]

  • Gokhin DS, Dubuc EA, Lian KQ, Peters LL, Fowler VM
    Alterations in thin filament length during postnatal skeletal muscle development and aging in mice
    Front Physiol. 2014 Sep 29;5:375. doi: 10.3389/fphys.2014.00375

    PMCID: PMC4178374

    [full text]

    [ eCollection 2014 ]

  • Grubb SC, Bult CJ, Bogue MA
    Mouse phenome database
    Nucleic Acids Res. 2014 Jan;42(Database issue):D825-34. doi: 10.1093/nar/gkt1159

    PMCID: PMC3965087

    [full text]

    [ Epub 2013 Nov 15 ]

  • Huang Y, Caputo CR, Noordmans GA, Yazdani S, Monteiro LH, van den Born J, van Goor H, Heeringa P, Korstanje R, Hillebrands JL
    Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice
    PLoS One. 2014 Mar 17;9(3):e91850. doi: 10.1371/journal.pone.0091850

    PMCID: PMC3956762

    [full text]

    [ eCollection 2014 ]

  • Moeller M, Hirose M, Mueller S, Roolf C, Baltrusch S, Ibrahim S, Junghanss C, Wolkenhauer O, Jaster R, Köhling R, Kunz M, Tiedge M, Schofield PN, Fuellen G
    Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching
    Aging Cell. 2014 Aug;13(4):729-38. doi: 10.1111/acel.12226

    PMCID: PMC4326954

    [full text]

    [ Epub 2014 May 23 ]

  • Mostafavi S, Ortiz-Lopez A, Bogue MA, Hattori K, Pop C, Koller D, Mathis D, Benoist C;
    Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains
    Immunological Genome Consortium. J Immunol. 2014 Nov 1;193(9):4485-96. doi: 10.4049/jimmunol.1401280

    PMCID: PMC4201955

    [full text]

    [ Epub 2014 Sep 29 ]

  • Noordmans GA, Huang Y, Savage H, van Dijk MC, Schaart G, van den Bergh Weerman MA, Heeringa P, Hillebrands JL, Korstanje R, van Goor H
    Genetic analysis of intracapillary glomerular lipoprotein deposits in aging mice
    PLoS One. 2014 Oct 29;9(10):e111308. doi: 10.1371/journal.pone.0111308

    PMCID: PMC4213026

    [full text]

  • Yu W, Ackert-Bicknell C, Larigakis JD, MacIver B, Steers WD, Churchill GA, Hill WG, Zeidel ML
    Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait
    Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1296-307. doi: 10.1152/ajprenal.00074.2014

    PMCID: PMC4042106

    [full text]

    [ Epub 2014 Apr 9 ]

2013

  • Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ
    High-precision genetic mapping of behavioral traits in the diversity outbred mouse population
    Genes Brain Behav. 2013 Jun;12(4):424-37. doi: 10.1111/gbb.12029

    PMCID: PMC3709837

    [full text]

    [ Epub 2013 Mar 20 ]

  • Noordmans GA, Caputo CR, Huang Y, Sheehan SM, Bulthuis M, Heeringa P, Hillebrands JL, van Goor H, Korstanje R
    Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene
    J Am Soc Nephrol. 2013 Dec;24(12):1995-2001. doi: 10.1681/ASN.2012080838

    PMCID: PMC3839541

    [full text]

    [ Epub 2013 Sep 5 ]

  • Strong R, Miller RA, Astle CM, Baur JA, de Cabo R, Fernandez E, Guo W, Javors M, Kirkland JL, Nelson JF, Sinclair DA, Teter B, Williams D, Zaveri N, Nadon NL, Harrison DE
    Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice
    J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):6-16. doi: 10.1093/gerona/gls070

    PMCID: PMC3598361

    [full text]

    [ Epub 2012 Mar 26 ]

  • Yuan R, Flurkey K, Meng Q, Astle MC, Harrison DE
    Genetic regulation of life span, metabolism, and body weight in Pohn, a new wild-derived mouse strain
    J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):27-35. doi: 10.1093/gerona/gls104

    PMCID: PMC3598364

    [full text]

    [ Epub 2012 May 8 ]

2012

  • Begley DA, Krupke DM, Neuhauser SB, Richardson JE, Bult CJ, Eppig JT, Sundberg JP
    The Mouse Tumor Biology Database (MTB): a central electronic resource for locating and integrating mouse tumor pathology data
    Vet Pathol. 2012 Jan;49(1):218-23. doi: 10.1177/0300985810395726

    PMCID: PMC3130112

    [full text]

    [ Epub 2011 Jan 31 ]

  • Flurkey K, Yuan R
    How the evolutionary theory of aging can guide us in the search for aging genes
    Aging (Albany NY). 2012 May;4(5):318-9

    PMCID: PMC3384432

    [full text]

    [ No abstract available ]

  • Kavirayani AM, Sundberg JP, Foreman O
    Primary neoplasms of bones in mice: retrospective study and review of literature
    Vet Pathol. 2012 Jan;49(1):182-205. doi: 10.1177/0300985811398252

    PMCID: PMC3151475

    [full text]

    [ Epub 2011 Feb 22 ]

  • Li Q, Berndt A, Guo H, Sundberg JP, Uitto J
    A novel animal model for pseudoxanthoma elasticum: the KK/HlJ mouse
    Am J Pathol. 2012 Oct;181(4):1190-6. doi: 10.1016/j.ajpath.2012.06.014

    PMCID: PMC3463623

    [full text]

    [ Epub 2012 Jul 28 ]

  • Maddatu TP, Grubb SC, Bult CJ, Bogue MA
    Mouse Phenome Database (MPD)
    Nucleic Acids Res. 2012 Jan;40(Database issue):D887-94. doi: 10.1093/nar/gkr1061

    PMCID: PMC3245053

    [full text]

    [ Epub 2011 Nov 18 ]

  • Murabito JM, Yuan R, Lunetta KL
    The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals
    J Gerontol A Biol Sci Med Sci. 2012 May;67(5):470-9. doi: 10.1093/gerona/gls089

    PMCID: PMC3326242

    [full text]

  • Schofield PN, Vogel P, Gkoutos GV, Sundberg JP
    Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice
    Dis Model Mech. 2012 Jan;5(1):19-25. doi: 10.1242/dmm.008334

    PMCID: PMC3255539

    [full text]

    [ Epub 2011 Oct 25 ]

  • Yuan R, Meng Q, Nautiyal J, Flurkey K, Tsaih SW, Krier R, Parker MG, Harrison DE, Paigen B
    Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains
    Proc Natl Acad Sci U S A. 2012 May 22;109(21):8224-9. doi: 10.1073/pnas.1121113109

    PMCID: PMC3361401

    [full text]

    [ Epub 2012 May 7 ]

2011

  • Lorenzo LP, Chen H, Shatynski KE, Clark S, Yuan R, Harrison DE, Yarowsky PJ, Williams MS
    Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress
    Antioxid Redox Signal. 2011 Oct 15;15(8):2083-94. doi: 10.1089/ars.2010.3798

    PMCID: PMC3166202

    [full text]

    [ Epub 2011 Jun 15 ]

  • Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, Wilkinson JE, Nadon NL, Strong R
    Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
    J Gerontol A Biol Sci Med Sci. 2011 Feb;66(2):191-201. doi: 10.1093/gerona/glq178

    PMCID: PMC3021372

    [full text]

    [ Epub 2010 Oct 25 ]

  • Schofield PN, Sundberg JP, Hoehndorf R, Gkoutos GV
    New approaches to the representation and analysis of phenotype knowledge in human diseases and their animal models
    Brief Funct Genomics. 2011 Sep;10(5):258-65. doi: 10.1093/bfgp/elr031

    PMCID: PMC3189694

    [full text]

  • Sher RB, Cox GA, Mills KD, Sundberg JP
    Rhabdomyosarcomas in aging A/J mice
    PLoS One. 2011;6(8):e23498. doi: 10.1371/journal.pone.0023498

    PMCID: PMC3154500

    [full text]

    [ Epub 2011 Aug 10 ]

  • Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, Deen PM, Korstanje R
    Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation
    Physiol Genomics. 2011 Mar 16;43(5):265-70. doi: 10.1152/physiolgenomics.00188.2010

    PMCID: PMC3068516

    [full text]

    [ Epub 2010 Dec 21 ]

  • Won J, Marín de Evsikova C, Smith RS, Hicks WL, Edwards MM, Longo-Guess C, Li T, Naggert JK, Nishina PM
    NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development
    Hum Mol Genet. 2011 Feb 1;20(3):482-96. doi: 10.1093/hmg/ddq494

    PMCID: PMC3016909

    [full text]

    [ Epub 2010 Nov 15 ]

  • Yuan R, Peters LL, Paigen B
    Mice as a mammalian model for research on the genetics of aging
    ILAR J. 2011;52(1):4-15

    PMCID: PMC3074346

    [full text]

2010

  • Flurkey K, Astle CM, Harrison DE
    Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice
    J Gerontol A Biol Sci Med Sci. 2010 Dec;65(12):1275-84. doi: 10.1093/gerona/glq155

    PMCID: PMC2990268

    [full text]

    [ Epub 2010 Sep 5 ]

  • Schofield PN, Gruenberger M, Sundberg JP
    Pathbase and the MPATH ontology. Community resources for mouse histopathology
    Vet Pathol. 2010 Nov;47(6):1016-20. doi: 10.1177/0300985810374845

    PMCID: PMC3038412

    [full text]

    [ Epub 2010 Jun 29 ]

  • Sundberg JP, Schofield PN
    Commentary: mouse genetic nomenclature. Standardization of strain, gene, and protein symbols
    Vet Pathol. 2010 Nov;47(6):1100-4. doi: 10.1177/0300985810374837

    PMCID: PMC3039125

    [full text]

    [ Epub 2010 Aug 4 ]

2009

  • Yuan R, Tsaih SW, Petkova SB, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B
    Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels
    Aging Cell. 2009 Jun;8(3):277-87. doi: 10.1111/j.1474-9726.2009.00478.x

    PMCID: PMC2768517

    [full text]

    [ Epub 2009 Apr 9 ]