Cross Sectional Study - Collaborative Cross (CC)

Cross Sectional Study - Collaborative Cross (CC)

Project Aims:

Characterization of healthspan and lifespan in CC mice investigating early, mid-life and late life biomarkers of aging. Establishment of a tissue bank to provide aged CC resources to the scientific community.

 

Project Start/End Dates: January 2016 - April 2018
Strain(s):

CC024/GeniUncJ (AU8004)

CC025/GeniUncJ (AU8008)

CC010/ GeniUncJ (AU8018)

CC026/GeniUncJ (AU8026)

CC042/GeniUncJ (AU8042)

CC051/TauUncJ (IL16912)

CC001/UncJ (OR13140)

CC002/UncJ (OR15156)

CC011/UncJ (OR3252)

Quantity/Sex/Age of animals:

Total: 201 animals in study

8 males and 8 females per cohort per strain.

6, 12, and 18 month timepoints

     

Animal Room

RAF B7 and RAF B8

Temperature: 72o F +/- 2

Link to JAX Animal Room Health Reports

Diet(s):

6% 5KOG

48 hour Fasting or Ad libitum (Control)

Phenotyping Assays: N/A
Animal Resources:

Muscle, Liver, Heart, Kidney, Spleen, Fat Pad, Blood Pellet

Link to Open Resources