DATA HIGHLIGHT : Age Differences in Heart Rate and Electrocardiogram Time Intervals
Center researchers characterizing inbred strains of mice for aging phenotypes at 6, 12 and 18 months of age have revealed a genetic influence on electrocardiogram (ECG) time intervals and heart rate in aging mice.
Data from these studies are presented below and have been deposited in the Mouse Phenome Database [ Datasets ]
Genetic influence on electrocardiogram time intervals and heart rate in aging mice
Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R.
Am J Physiol Heart Circ Physiol. (2009) 296(6): H1907-13. PMCID: PMC2716104 [ Full Text ]
Examples of age differences in heart rates for C57L/J (C57L) females and BALB/cByJ (BALB) males (A) and in electrocardiogram time intervals: P-R intervals in 129S1 females (B) and QRS intervals in C57BR/cdJ (C57BR) males (C). Graphs show means +/- SD.